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THE SUPERIORITY OF SEAL OIL
Seal oil is a superior source of Omega-3 compared to fish in many ways. DPA is present at very low levels in fish oils relative to EPA or DHA but is almost as important as either the EPA or the DHA. Harp Seal oil can supply up to 10(ten) times more DPA than fish oils, About a third of the long-chain Omega-3 fatty acids circulating in human blood is attributable to DPA. Because of this, DPA has become of interest to medical researchers in both France and Japan. It seems that in the blood vessel walls, EPA may actually be converted to DPA as the effective agent. Japanese researchers at the Tokyo Medical and Dental University in Tokyo have shown that the one stimulating effect of EPA is the key in producing prostaglandin that keeps the artery wall soft and free of plaque, this study indicates that DPA may be 10 ~ 20 times more powerful than EPA in this effect. Harp Seal Oil is the ONLY supplement rich in natural DPA.
With the exception of seal oil, the highest incidence of DPA is in human breast milk. Deficiencies in Omega-3 PUFA? such as DPA may result in impaired development of visual acuity and motor skills, according to several studies. The relative proportions of Omega-3 PUFA in most fish oils does not correspond well with that of human breast milk, but Harp Seal Oil into the human body is easier and more thorough than fish oils. In Harp Seal Oil, the Omega-3 fatty acids are in the -1 and -3 positions of the triglyceride molecule (same as humans) while in fish oil they are in the -2 position. The Omega-3 content of Harp Seal Oil is 20% ~ 25%, which is higher than most fish oils, making Harp Seal Oil supplement a much more effective source of Omega-3 than fish itself. Harp Seal Oil is virtually free of cholesterol, while many fish and fish oils are relatively high in cholesterol. Fish oil is susceptible to oxidization whereas Harp Seal Oil is more resistant to natural oxidative processes. Preliminary experiments by Drs. Nakhla and David have shown that the extent of oxidization of Omega-3 PUFA in Harp Seal in vitro was less than half observed in fish oils.
OMEGA-3 IN DISEASE PREVENTION
Omega-3 PUFA? decreases plasma lipids through reduced synthesis of fatty acids and very low-density lipoproteins (VLDL). They also have a direct effect on the heart muscle, increase blood flow, decrease arrhythmias, improve arterial compliance, decrease the size of the infarct and reduce several cellular processes that compromise heart function. It has also been suggested that marine oils may retard atherosclerosis through their effects on platelet function, platelet-endothelial interactions and inflammatory response.
Heart disease:
Research has indicates that Omega-3 can reduce the risk of primary cardiac arrest by 70%, by reducing blood vessel blockages. Other work (Dr. Leof of Harvard Medical School) has found that PUFA? can prevent sudden death from irregular heartbeats following a heart attack. Another study has found that a diet rich in Omega-3 can reduce chances of a second (fatal) heart attack by 30%. The results are primarily from the fact that Omega-3 makes the walls of the blood vessel blockages that are often the cause of heart problems.
Mental illness:
A British study claims that up to 80% of schizophrenics are deficient in unsaturated fatty acids like Omega-3. Omega-3 deficiency has also been linked to depression and general mental deterioration.
Arthritis:
More than a dozen studies confirm that Omega-3 offers anti-inflammatory relief for arthritis suffers.
Diabetes:
A disorder characterize by high blood levels of glucose in the blood. Diabetes can damage the large blood vessels increasing the risk of stroke, heart attack, and in the limbs, gangrene. Many studies now suggest that Omega-3 is invaluable in combating circulation problems associated with diabetes by rendering the walls of the veins and arteries smoother and more elastic.
Reduces Cholesterol:
A person with a high level of cholesterol came to the National Hospital in Nuuk. He had tried different diets and medical treatment, but his cholesterol count was still higher than was it was before, he was urged to eat only traditional Greenland food (Harp Seal Meat, Fat). In just a month his cholesterol count fell by a whole 70%.
Many studies have been undertaken on the positive effects of marine oils. While most of these focused on fish oils, it must be stated that in relationship to Omega-3, seal oil is the superior marine oil.
Orsoq Seal Research Project: Dr. E. Jorgenson of the Center of Arctic Environmental Medicine in Denmark recently presented the initial results of the Orsoq Seal Research Project, a pilot study on the effect of seal oil on human health These preliminary findings indicate that the general population of Denmark, fed on a modern diet, was ten times more likely to develop cardiovascular and inflammatory diseases that Greenlanders on their traditional diet of seal, a food high in omega-3. "Inuit Whaling", Inuit Circumpolar Conference, June 1992, special issue. Gerth Mulved and Henning Sloth Pederson, Doctors of Medicine Dronning Ingrids Hospital.
Seal Oil & Cholesterol: Dr. Garth Mulvad and Dr. Henning Pederson of the Department of Medicine. Dronning Ingrids Hospital in Norway noted that fish eating nations have, on average, a higher cholesterol level than the Inuit. However, they suggest that a diet including marine mammal oils decreases cholesterol levels. There is a growing body of evidence showing the positive effects of omega 3 in our diets. In a 1950 study conducted at Camp Hill Hospital Halifax, Nova Scotia, the effect of seal oil on patients with atherosclerosis and hypercholesterolemia was studied. The results showed that taking seal oil reduced cholesterol by 20%. (Ackman, Safety of Seal oil as Nutritional Supplement, Proc, NS Inst. of Sci. (1997) - Vol. 41, part 3, 103-114)
Modulation of atherosclerotic risk factors by seal oil: a preliminary assessment.
Bonefeld-Jorgensen EC, Moller SM, Hansen JC. Department of Environmental and Occupational Medicine, University of Aarhus, DK-8000, Aarhus, Denmark. ebj@mil.au.dk ?xamined whether dietary supplementation with seal oil influenced the risk factors of atherosclerosis in healthy volunteers. Two intervention studies were carried out as preliminary steps in a larger project which aim at elucidating the disease preventive potential of seal oil. ?In both studies plasma triglyceride and the n-6/n-3 fatty acid ratio of plasma and erythrocytes were significantly reduced upon seal oil intake.
The International Atherosclerosis Project (1992): Since 1990, researchers from the Louisiana State University have analyzed the coronary arteries of 23,000 deceased persons from 16 countries. The interim results reveal that the Greenlanders have the lowest rate of atherosclerosis among all those tested. Some of the fascinating early results are as follow:
The Inuit who ate a modern diet had the same rate of this disease as ordinary Europeans and therefore the results were not based on heredity.
The Inuit who lived on a traditional diet of marine mammals (mainly seal) had, at the age of seventy, the same coronary artery elasticity as a 20 year old European. Some European countries may eat more fish than is found in the traditional Greenland diet, but have a far higher incidence of atherosclerosis and, in general, higher levels of cholesterol.
Coronary Heart Disease and Hyperlipidemia: Studies have found a strong relationship between the fatty acids ALA, EPA, and DHA and reduced occurrence of coronary heart disease and atherosclerosis, a disease in which a plaque-like substance forms on the blood vessel walls. Fish oil can decrease the risk of coronary heart disease and heart attacks. A large number of clinical trials have established that both EPA and DHA reduce blood triglycerides by 25-30 percent.
It is also well documented that regular consumption of fish oil reduces platelet adhesion and aggregation, and prevents blood clotting. (2 & 3 )
Arrhythmia: Cardiac arrhythmia is the broad term applied to disorders characterized by an irregular heartbeat. The severity of this condition can range from mild to critical, where the heart may stop beating completely. Arrhythmia is responsible for Sudden Cardiac Death syndrome and follows many so-called "heart attacks". There is strong clinical evidence suggesting the protective role of fish oil for this condition. Studies have identified the most anti-arrhythmic component of fish oil as DHA or its combination with EPA. (4 )
Hypertension: The blood pressure lowering effects of dietary fish oil have been well evaluated by a meta-analysis of 31 placebo- controlled trials comprising 1,356 patients. (5) Fish oil? effect appears greater in patients with high blood pressure.
Arthritis: Abnormal fatty acid levels and decreased levels of EPA occur in patients with rheumatoid arthritis.(6) Not surprisingly, fish oil supplementation can normalize these levels. Numerous studies have shown that supplementation consistently reduces joint inflammation and tenderness, and reduces the duration of morning stiffness. (7) Patients have also been able to significantly reduce their intake of NSAIDs (non steroidal anti-inflammatory drugs) and other drugs used to treat arthritis. In fact, some patients were able to discontinue their other medication completely, without having a flare up. (8,9) Furthermore, animal studies have shown that fish oil supplementation protects against gastric ulceration, a common side effect of NSAIDs.(10) Recent research has uncovered even better news ?supplementation may offer protection against cartilage destruction that normally occurs during the disease. (11)
Skin Disease: Essential fatty acids are well known to improve many skin disorders, including dry, itchy, inflamed skin. These good fats improve the barrier function of the skin and help prevent moisture loss. Fish oil supplementation is especially effective in the treatment of psoriasis. (12,13) Even increasing dietary consumption of oily fish has proven beneficial in combating psoriasis. (14)
Mental disorders: Currently scientists predict that fish oil may alleviate certain mental disorders. A group of 16 patients with bipolar disorder ("manic depression") who took fish oil for four months experienced much longer periods of remission than those given a placebo. Only 13 percent of patients receiving fish oil experienced the recurrence of mania or depression, compared to more than 50 percent in the placebo group. A group of researchers from the United Kingdom also found that schizophrenic patients who consume more ALA, DHA and EPA in their diet or receive them as supplements have less severe symptoms. Studies suggest that depression may also be related to insufficient amounts of these EFAs. (15, 16) Deficiency of ALA, EPA and DHA also plays a role in a significant number of other mental disorders including aggression, depression, dementia, and Attention Deficit Hyperactivity Disorder.
Diabetes: Individuals with diabetes may benefit from fish oil supplementation for several reasons. Although the effect of fish oil on blood glucose levels is controversial, both epidemiological and animal studies indicate that high fish consumption may reduce the incidence of diabetes. (17,18) Secondly, supplementation clearly has numerous positive effects for the diabetic through reduction of triglycerides, blood pressure, and platelet aggregation. Thirdly, supplementation may provide a protective effect on nerve function ?to help protect against diabetic neuropathy, a degenerative complication of diabetes.(19)
Multiple Sclerosis: There is considerable statistical evidence that the incidence of multiple sclerosis varies in countries where the diet differs. This data seems to show that the presence of ALA, EPA, and DHA may result in a lower incidence of this disease. A study published in 1989 looked at the long-term effects of ALA, EPA, and DHA in the treatment of multiple sclerosis. (20) The study concluded that there were improvements in the treated group when compared to the control group in terms of duration, frequency and severity of relapses and the number of patients who either improved or remained unchanged.
Cancer: In some studies, it has been hypothesized that highly unsaturated fatty acids, found primarily in fish oil, could be used as a protective agent against certain cancers. Some studies on animals have shown that these fatty acids may decrease both the number and size of tumours; however the studies are still in the early stages. (21)
Crohn Disease: A recent study has shown the effectiveness of fish oil in the maintenance of remission of Crohn? disease. Fifty patients were treated with an ALA, EPA, and DHA mixture or a placebo for 12 months. After the study was completed the rate of severe recurrences in the group treated with fish oil was 34 percent compared to 62 percent in placebo-treated patients. (22)
Pregnancy and Fetal Health: There is a small but noticeable worldwide tendency towards shorter pregnancies, which may have a negative effect on fetal development. It is suggested that an EFA deficiency may be responsible for the change. A study has shown that a diet rich in ALA, DHA and EPA may help lengthen pregnancy. Danish women who were given fish oil during their third trimester prolonged their pregnancies by four days. Fetuses, particularly in the third trimester, also require DHA to facilitate the development of brain and retinal tissue. (23)
Child Development: DHA makes up 15-20 percent of the fat in the brain and 30-60 percent of the fat in the retina. Studies show that children who receive sufficient amounts of DHA are intellectually "better off" than children who are deficient. (24, 25)
Lupus Erythematosus (LE): Lupus has symptoms ranging from minor skin disorders to severe kidney damage. Several investigations have indicated that fish oil could have a favourable effect on the disease. A 34-week, double-blind study was done involving 34 patients with lupus. Fourteen of the 17 patients using fish oil saw their condition improve, while 13 from the placebo group were rated worse or experienced no change. (7)
IgA Nephropathy: Mesangial IgA nephropathy is a common disease of the kidney, which usually causes renal failure within 10 to 20 years. A treatment that can help prevent renal failure in IgA nephropathy has not yet been found. However, some studies suggest that fish oil may have a beneficial effect in slowing the progression of this disease. Fish oil has been reported to prevent deterioration of renal function in experimental models of the disease. (26, 27)
References:
1. Bang, H.O., Dyerberg, J., Hjoorne, N. The composition of food consumed by Greenland Eskimos. Acta Medica Scandinavica, Vol. 200, pp 69-73, (1976).
2. Harris, W.S. n-3 Fatty acids and serum lipoproteins: human studies American Journal of Clinical Nutrition, Vol. 65 (suppl): pp 1645S-54S, (1997).
3. Willatts P., et al. Effect of long-chain polyunsaturated fatty acids in infant formula on problem solving at 10 months of age. Lancet, Vol. 352, pp 688-691, (1998).
4. Hursting S.D., et al. Types of dietary fat and the incidence of cancer at five sites. Prevention Medicine, Vol. 19, pp 242 253, (1990).
5. Appel L.J., et al. Does Supplementation of Diet with ?ish Oil?Reduce Blood Pressure? A Meta-analysis of Controlled Clinical Trials. Archives of Internal Medicine, Vol. 153 (12), pp 1429-38, (1993).
6. Navarro E, Esteve M, Olive A, Klaassen J, Cabre E, Tena X, Fernandez-Banares F, Pastor C, Gassull MA Abnormal fatty acid pattern in rheumatoid arthritis. A rationale for treatment with marine and botanical lipids. Journal of Rheumatology, 2000 Feb;27(2):298-303.
7. Kremer JM. n-3 fatty acid supplements in rheumatoid arthritis. American Journal of Clinical Nutrition, 2000 Jan;71(1 Suppl):349S-351S.
8. Kremer JM, Lawrence DA, Petrillo GF, Litts LL, Mullaly PM, Rynes RI, Stocker RP, Parhami N, Greenstein NS, Fuchs BR et al. Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs. Clinical and immune correlates. Arthritis and Rheumatism, 1995;38(8):1107-1114.
9. Lau CS, Morley KD, Belch JJ. Effects of fish oil supplementation on non- steroidal anti-inflammatory drug requirement in patients with mild rheumatoid arthritis - a double-blind placebo controlled study. British Journal Rheumatology, 1993;32:982-989.
10. Manjari V, Das UN Effect of polyunsaturated fatty acids on dexamethasone- induced gastric mucosal damage. Prostaglandins Leukotrienes and Essential Fatty Acids, 2000 Feb;62(2):85-96.
11. Curtis CL, Hughes CE, Flannery CR, Little CB, Harwood JL, Caterson B. n-3 fatty acids specifically modulate catabolic factors involved in articular cartilage degradation. Journal of Biological Chemistry, 2000 Jan. 14;275(2):721-724.
12. Grimminger F, Mayser P, Papavassilis C, Thomas M, Schlotzer E, Heuer KU, Fuhrer D, Hinsch KD, Walmrath D, Schill WB, et al . A double-blind, random ized, placebo-controlled trial of n-3 fatty acid based lipid infusion in acute, extended guttate psoriasis. Rapid improvement of clinical manifestations and changes in neutrophil leukotriene profile. Clinical Investigation, 1993 Aug. 71(8):634-643.
13. Gupta AK, Ellis CN, Tellner DC, Anderson TF, Voorhees JJ. Double-blind, placebo-controlled study to evaluate the efficacy of fish oil and low-dose UVB in the treatment of psoriasis. British Journal of Dermatology, 1989 June;120(6):801-7.
14. Collier PM, Ursell A, Zaremba K, Payne CM, Staughton RC, Sanders T. Effect of regular consumption of oily fish compared with white fish on chronic plaque psoriasis. European Journal of Clinical Nutrition, 1993 Apr;47(4):251-254.
15. Hibbein J. Fish consumption and major depression. Lancet, Vol. 351,pp 1213, (1998).
16. Stoll A.L., et al. Omega 3 Fatty Acids in Bipolar Disorder. A Preliminary Double- blind, Placebo-Controlled Trial. Archives of General Psychiatry, Vol. 56, pp 407- 412, (1999).
17. Adler AI, Boyko EJ, Schraer CD, Murphy NJ. Lower prevalence of impaired glucose tolerance and diabetes associated with daily seal oil or salmon consumption among Alaska Natives. Diabetes Care,1994;17:1498-1501.
18. Nobukata H, Ishikawa T, Obata M, Shibutani Y. Long-term administration of highly purified eicosapentaenoic acid ethyl ester prevents diabetes and abnor- malities of blood coagulation in male WBN/Kob rats. Metabolism, 2000 Jul;49(7):912-9
19. Gerbi A, Maixent JM, Barbey O, Jamme I, Pierlovisi M, Coste T, Pieroni G, Nouvelot A, Vague P, Raccah D. Neuroprotective effect of fish oil in diabetic neuropathy. Lipids, 1999;34, S93-94.
20. Bates D., et al. A double-blind controlled trial of long chain n-3 polyunsaturated fatty acids in the treatment of multiple sclerosis. Journal of Neurology and Psychiatry, Vol. 52(1), pp18-22, (1989).
21. Hursting S.D., et al. Types of dietary fat and the incidence of cancer at five sites. Prevention Medicine, Vol. 19, pp 242 253, (1990).
22. Belluzzi, A., et al. Effect of an enteric-coated fish-oil preparation on relapses in Crohn? disease. New England Journal of Medicine, Vol. 334, pp 1557-1560, (1996).
23. McLennan P., et al. The cardiovascular protective role of docosahexaenoic acid. European Journal of Pharmacology, Vol. 300, pp 83-89, (1995).
24. Anderson g.l., Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina. Pediatric Research, Vol. 27 (1), pp 89- 97, (1990).
25. Walton A.J., et al. Dietary fish oil and the severity of symptoms in patients with systemic lupus erythematosus. Annals of the Rheumatic Diseases, Vol. 50 (7), pp 467-466, (1991).
26. Bennet W.M., et al. Treatment of IgA nephropathy with eicosapentanoic acid (EPA): a two year prospective trial. Clinical Nephrology, Vol. 31, pp 128-131, (1989).
27. Fung S.M. et al. Fish oil therapy in IgA Nephropathy. Annals of Pharmacy, Vol. 31, pp 112-115, (1997).
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About Us
We focuses on the full utilization and development of high quality products, from the renewable Harp seal resource abundant in the waters off the coast of Newfoundland. NUTRICAN products include Omega-3 rich Harp seal oil supplied in bulk oil or capsule form, and processed seal meat. The oil is extracted from the blubber of the animal and marketed internationally.
The health benefits of Omega-3 have been well documented by various scientific journals and initial research conducted by ...
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